長田　洋子


　論　文
  1. Nagata, Y. Ito, T. (1983) Turk液または酸性クリスタルバイオレット液染色法による細胞数計
    測時にみられる誤差について．臨床検査 27, 914-916
  2. Onodera, T., Sato, H., Nagata, Y. (1984) Biochemical characterization of the
    materials accumulated in the alveoli of patients with alveolar proteinosis.
    Sapporo Med. J. 53, 471-491.　
  3. Nagata, Y., Kohsaka, K., Ito, T. (1985) Negative observations on immunological
    side effects of rifampin and dapsone in mice. Int. J. Leprosy 53, 421-427.
  4. Nagata, Y., Akino, T., Ohno, K. (1985) Microdetermination of serum D- amino
    acids. Anal. Biochem. 150, 238-242.
  5. Nagata, Y., Akino, T., Ohno, K., Kataoka, Y., Ueda, T., Sakurai, T., Shiroshita, K.,
    Yasuda, T. (1987) Free D-amino acids in human plasma in relation to senescence
    and renal diseases. Clin. Sci. 73, 105-108.
    　
  6. 長田洋子, 秋野豊明, 大野公吉, 片岡是充, 上田峻洋, 桜井哲男, 城下弘一, 安田卓二
    （１９８７, ８月） ヒト血漿遊離D-アミノ酸値と腎機能障害の程度. 医学のあゆみ　１４２,　４０１
    −４０２．
  7. Nagata, Y., Akino, T. (1988) D-Amino acid oxidase in mouse liver. Comp. Biochem.
    Physiol. 898, 179-182.
  8. Nagata, Y., Shimojo, T., Akino, T. (1988) D-Amino acid oxidase in mouse liver II.
    Comp. Biochem. Physiol. 918, 503-504.
    　
  9. Nagata, Y., Shimojo, T., Akino, T. (1988) Two spectrophotometric assays for D-
    amino acid oxidase : For the study of distribution patterns. Int. J. Biochem. 20,
    1235-1238.
  10. Nagata, Y., Konno, R., Yasumura, Y., Akino, T. (1989) Involvement D- amino acid
    oxidase in elimination of free D-amino acids in mice. Biochem. J. 257, 291-292.
    　
  11. Yamada, R., Nagasaki, H., Nagata, Y., Wakabayashi, W., Iwashima, A. (1989)
    Administration of D-aspartate increases D-aspartate oxidase activity in mouse
    liver. Biochim. Biophys. Acta 990, 325-328.
  12. Nagata, Y., Akino, T., Ohno, K. (1989) The presence of free D-amino acids in mouse
    tissues. Experientia 45, 330-332.
  13. Konno, R., Nagata, Y., Niwa, A., Yasumura, Y. (1989) Spontaneous excretion of
    D-alanine in urine in mutant mice lacking D-amino acid oxidase. Biochem. J. 269,
    285-287.
    　
  14. 長田洋子 （１９８９, ８月） 生体に存在するD-アミノ酸：哺乳類を中心として．札幌医学雑誌
    　５８,　２７１−２７８．
  15. Nagata, Y., Akino, T. (1990) D-Amino acids in mouse tissues are not of microbial
    origin. Experientia 46, 466-468.
    　　
  16. 長田洋子 （１９９１, ９月） 高等動物哺乳類に存在するD-アミノ酸 Viva Origino．１８,　
    １３１−１４３．
  17. Nagata, Y., Nagasaki, H., Yamada, R., Konno, R., Yasumura, Y. (1991)
    Administration of D-alanine did not cause increase of D-amino acid　oxidase activity
    in mice. Experientia 47, 835-838.
  18. Nagata, Y., Yamamoto, K., Shimojo, T. (1992) Determination of D- and L- amino
    acids in mouse kidney by high-performance liquid chromatography.
    J. Chromatogr. 575, 147-152.
    　　
  19. Nagata, Y., Yamamoto, K., Shimojo, T., Konno, R., Yasumura, Y., Akino, T. (1992)
    The presence of free D-alanine, D-proline and D-serine in mice. Biochim. Biophys.
    Acta 1115, 208-211.
    　
  20. Nagata, Y. (1992) Involvement of D-amino acid oxidase in elimination of D-serine
    in mouse brain. Experientia 48, 753-755.
  21. Nagata, Y., Masui, R., Akino, T. (1992) The presence of free D-serine, D- alanine
    and D-proline in human plasma. Experientia 48, 986-988.
    　
  22. 長田洋子,　山本和彦 (１９９２, 12月) 高速液体クロマトグラフィーによるD-,　L-アミノ酸の
    分離定量． 生化学 ６４, １４５１−１４５３. 　（長田他１名との共著）
  23. Nagata, Y., Kubota, K. (1992) A trial to determine D-amino acids in tissue
    proteins of mice. Amino Acids 4, 121-125.
    　　
  24. Nagata, Y., Horiike, K., Maeda, T. (1994) Distribution of free D-serine in
    vertebrate brains. Brain Res. 634, 291-295.
    　
  25. Nagata, Y., Konno, R., Niwa, A. (1994) Amino acid levels in D-alanine-
    administered mutant mice lacking D-amino acid oxidase. Metabolism 43, 1153-
  26. Nagata, Y., Borghi, M., Fisher, G., DｹAniello, A. (1995) Free D-serine concentration
    in normal and Alzheimer human brain. Brain Res. Bull. 38, 181-183.
    　
  27. Nagata, Y., Shoji, R., Yonezawa, S., Oda, S. (1997) Brain D-serine and tyrosine
    levels in ataxic mutant mice. Amino Acids 12, 95-100.
    　
  28. 長田洋子 （１９９７） 高等動物哺乳類に存在するD-アミノ酸．　Viva Origino ２５,　
    ６１−７２． 平成９年６月　
  29. Nagata, Y., Fujiwara, T., Kawaguchi-Nagata, K., Fukumori, Y., Yamanaka, T.
    (1998) Occurrence of peptidyl D-amino acids in soluble fractions of several
    eubacteria, archaea and eukaryotes. Biochim. Biophys. Acta 1379, 76-82.
    　
  30. Nagata, Y., Uehara T., Kitamura, Y., Nomura, Y., Horiike, K. (1998) D- Serine
    content and D-[3H]serine binding in the brain regions of the senescence-accelerated
    mouse. Mech. Ageing Dev. 104, 115-124.
    　　　
  31. Nagata, Y., Tagashira J. (1998) Rate of racemization and degradation of amino
    acids during acid-hydrolysis of synthetic peptides. Viva Origino 26, 321-328.
  32. Nagata, Y., Tanaka, K., Iida, T., Kera, Y., Yamada, R., Nakajima, Y., Fujiwara, T.,
    Fukumori, Y., Yamanaka, T., Koga, Y., Tsuji, S., Kawaguchi-Nagata, K. (1999)
    Occurrence of D-amino acids in a few archaea and dehydrogenase activities in
    hyperthermophile Pyrobaculum islandicum. Biochim. Biophys. Acta 1435, 160-
    166.
  33. Inoue, N., Sonobe, S., Nagata, Y., Shimmen, T. (1999) Secretion of lectin-binding
    material in rhizoid differentiation of Spyrogyra. Plant Cell Physiol. 40, 973-977.
    　
  34. 長田 洋子 (２０００)　 自然界に存在するD-アミノ酸．生化学 ７２,　１７３−１８０.
    平成１２年３月　　　　　　　　
  35. Nagata, Y., Iida, T., Sakai, M. (2001) Enantiomeric resolution of amino acids by thin-layer chromatography. J. Mol. Catal. B: Enzymatic 12, 105-108
  36. Nagata, Y., Fukuda, A., Sakai, M., Iida, T., Kawaguchi-Nagata, K. (2001) D-Amino acid contents of mitochondria and some purple bacteria. J. Mol. Catal. B: Enzymatic 12, 109-113
    　
  37. Inoue, N., Yamada, S., Nagata, Y., Shimmen, T. (2002) Rhizoid differentiation in Spyrogyra: Position sensing by terminal cells. Plant Cell Physiol. 43, 470-483.

　著　書

　1. Nagata, Y. (1999) D-amino acids in nature.
　 　Advances in Biochirality (G. Palyi, C. Zucchi, L. Caglioli, Eds.)
　　(G. Palyi, C. Zucchi, L. Caglioli編) p.271-283. Elsevier Sciences (Oxford, UK).


　

西村 克史

　
論　文

Stereospecificity of Reactions Catalyzed by Bacterial D-Amino Acid Transaminase,
Martinez del Pozo, A., Merola, M., Ueno, H., Manning, J. M., Tanizawa, K., Nishimura, K., Soda, K., & Ringe, D. (1989).
J. Biol. Chem., 264, 17784-17789.

Effect of D-Serine on Bacterial D-Amino Acid Transaminase: Accumulation of an Intermediate and Inactivation of the Enzyme,
Martinez del Pozo, A., Pospischil, M. A., Ueno, H., Manning, J. M., Tanizawa, K., Nishimura, K., Soda, K., Ringe, D., Stoddard, B., & Petsko, G. A. (1989).
Biochemistry, 28, 8798-8803.

Activity and Spectroscopic Properties of Bacterial D-Amino Acid Transaminase After Multiple Site-Directed Mutagenesis of a Single Tryptophan Residue,
Martinez del Pozo, A., Ueno, H., Manning, J. M., Tanizawa, K., Nishimura, K., Asano, S., Tanaka, H., Soda, K., Ringe, D., & Petsko, G. A. (1989).
Biochemistry, 28, 510-516.

Bacterial D-Amino Acid Transaminase -Stereospecificity of Reaction Pathway, Spectral Effects, and Inactivation Generated By D-Serine.
Maning, J. M., Martinez del Pozo, A., Ueno, H., Tanizawa, K., Nishimura, K., Soda, K., Ringe, D., Stoddard, B., & Petsko, G. (1990. 5)
Annals of The New York Academy of Sciences, 585, 516-518

Effect of Substitution of a Lysyl Residue that Binds Pyridoxal Phosphate in thermostable D-Amino Acid Aminotransferase by Arginine and Alanine,
Nishimura, K., Tanizawa, K., Yoshimura, T., Esaki, N., Futaki, S., Manning, J. M., & Soda, K. (1991).
Biochemistry, 30, 4072-4077.

Unique Stereospecificity of D-Amino Acid Aminotransferase and Branched-Chain L-Amino Acid Aminotransferase for C-4' Hydrogen Transfer of the Coenzyme,
Yoshimura, T., Nishimura, K., Ito, J., Esaki, N., Kagamiyama, H., Manning, J. M., & Soda, K. (1993).
the Journal of the Americal Chemical Society, 115, 3897-3900.

A Simple Method for Determination of Stereospecificity of Aminotransferases for C-4' Hydrogen Transfer of The Coenzyme,
Nishimura, K., Ito, J., Yoshimura, T., Esaki, N., & Soda, K. (1994).
Bioorganic & Medicinal Chemistry, 2, 605-607.

酵母ポリサッカライドの土壌改良効果
長沼孝文、小林憲治、新井康裕、西村克史、兎束保之 (1997)
作物栄養研究会誌、46、1-12.

Development of a New Chemically Defined Sporulation Medium for the Yeasts in the Genus Lipomyces,
Watanabe H., Okada M., Hibi T., Nishimura, K., Naganuma T., & Uzuka Y. (1997).
J. Gen. Appl. Microbiol., 43, 289-293.

酵母ポリサッカライドの土壌改良効果第２報-ポリサッカライド添加物による土壌の物理的性質の変化および栽培実験-
新井康裕、角田テレサ、秋山康三、西村克史、長沼孝文、兎束保之 (1998)
作物栄養研究会誌、47、9-24.

An Improved Method for Isolating Yeasts in the Genus Lipomyces and Related Genera from Soil,
Naganuma T., Katsumata K., Ando T., Watanabe H., Nishimura K., & Uzuka Y. (1999).
Biosci. Biotechnol. Biochem., 63, 195-198

Biodegradation of triazine herbicides on polyvinylalcohol gel plates by the soil yeast Lipomyces starkeyi
Katsushi Nishimura, Masaki Yamamoto, Tomoko Nakagomi, Yumiko Takiguchi, Takafumi Naganuma, and Yasuyuki Uzuka (2002)
Appl. Microbiol. Biotechnol., 58, 848-852

Total DNA Preparation Excluding Extracellular Acidic Polysaccharide from Lipomyces Yeasts and its Application to Taxonomic Studies
Katsushi Nishimura, Koji Shimada, Hiroki Iwasawa, Takafumi Naganuma, and Yasuyuki Uzuka (2002)
Biosci. Biotechnol. Biochem., 66, 1563-1566

Proceedings


Site-Directed Mutagenesis of the Active-Site Lysine Residue of Thermostable D-Amino Acid Aminotransferase.
Nishimura, K., Tanizawa, K., & Soda, K. (1989. 8)
In the 5th FAOB Congress (p364) Seoul.

Effect of Substitution of a Lysyl Residue that Binds Pyridoxal Phosphate in thermostable D-Amino Acid Aminotransferase by Arginine and Alanine.
Nishimura, K., Tanizawa, K., Yoshimura, T., Esaki, N., Manning, J. M., & Soda, K. (1991. 10. 16).
In the First International Congress on Vitamines and Biofactors in Life Science, (p. 82). Kobe.


　総説・解説・資料

耐熱性 D-アミノ酸トランスアミナーゼ：タンパク工学的手法による活性中心構造の解析と分子進化論的考察
西村克史、谷沢克行、左右田健治 (1990. 1). バイオサイエンスとインダストリー, 48, 11-18.

良く切れる RNA 制限酵素
西村克史 (1994. 1).生物工学会誌, 72, 36.

脳の目的？
西村克史 (2001. 2) 、山梨新報：なるほどサイエンス（2月16日）


　著　書

Thermostable D-Amino Acid Aminotransferase: Substitution of Arginyl and Alanyl Residues for Lysine 145,
Nishimura, K., Tanizawa, K., Yoshimura, T., Esaki, N., Manning, J. M., & Soda, K. (1991).
In T. Fukui, H. Kagamiyama, K. Soda, & H. Wada (Eds.), Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors (pp. 215-216). Oxford: Pergamon Press.

土壌酵母による残留農薬の分解
西村克史 (1995. 1). In 第４回テレビ山梨サイエンス振興基金研究報告書 (pp. 61-67). 甲府市: テレビ山梨厚生文化事業団.

タンパク質低コスト生産システムの構築
西村克史 (1997. 3). In 研究報告集14 (pp. 107-109). 東京都: 実吉奨学会.

生化学辞典 第三版
(1998.10) 分担執筆、東京化学同人

生物工学実験書 改訂版
(2002.4) 分担執筆、日本生物工学会編、培風館


　　特　許



　 口 頭 発 表


谷川　　実


　論　文

The regulation by ATP of the catalytic activity and molecular state of Thiobacillus novellus cytochrome c oxidase.
Shoji,K., Hori,K., Tanigawa,M. & Yamanaka,T.
In Oxygen Homeostasis and Its Dynamics (Ishimura,Y., Shimada,H. & Suematsu,M., eds.) Springer-Verlag Tokyo, pp.120-124.(1998).

The effects of several nucleotides on the molecular state and catalytic activity of Thiobacillus novellus cytochrome c oxidase. ATP affectc the oxidase uniquely
K.Shoji, M.Tanigawa, K.Hori, Y.Tomozawa, T.Yamanaka
Eur. J. Biochem., 264, 960-964 (1999).

下水処理施設の被腐食コンクリート中に生息する細菌とその生育に対するギ酸カルシウムの阻害作用
山中健生、阿曽巌、富樫俊介、宮坂秀一、小川淳子、佐藤岳洋、田中尚子、飯野絵理子、井上誉士、大山展孝、尾崎めぐみ、中村晴幸、神庭朋裕、原郁子、藤平裕子、谷川実、庄子和夫、渡辺嗣道、渡辺直樹、青木治雄、牧和郎、鈴木宏
日本大学理工学研究所所報, No.89, 485-493 (2000).

The effect of ATP on the dimer-monomer conversion of Thiobacillus novellus cytochrome c oxidase
Minoru Tanigawa, Hiroki Makiguchi, Shin-ichi Tobe, Kazuo Shoji and Tateo Yamanaka
Biochem. Biophys. Acta EBEC Short Reports, 11, 225 (2000)

The cyanide binding reaction of bovine cytochrome c oxidase is affected by AMP and ADP
Tetsuya Yamato, Kazuo Shoji, Alessandro Giuffre, Emilio D'Itri, Minoru Tanigawa, Tateo Yamanaka, Paolo Sarti, Maurizio Brunori
Biochem. Biophys. Acta EBEC Short Reports, 11, 220 (2000)

　 口 頭 発 表